Protosqualus was a genus of dogfish shark that existed during the Cretaceous. Fossils have been found in Europe, East Asia, Antarctica, Australia, India and South America. The type species is Protosqualus sigei, which was found around an Albian aged deposit in France. There are 6 species which can be differentiated by distinct features in their teeth. Some species show some level of heterodonty, for example Protosqualus barringtonensis shows a rather high level of heterodonty within its teeth. The oldest specimens are from the Speeton Clay Formation. Protosqualus teeth are quite common in the Grey Chalk deposit of England. The genus went extinct at the end of the Cretaceous during the Cretaceous–Paleogene extinction event, with the last species in the genus being Protosqualus argentinensis from southern Argentina as well as possibly being from earlier deposits in India.