In June 2019, Medrano stated that she was working with Erica Lindbeck, Brock Baker, and Brandon Rogers on a "new project". The
pilot of
Helluva Boss was cast by voice actor
Kellen Goff and voice directed by Medrano and Rick Zieff. Lucas Bermudez of
Screen Rant attributed the success of
Hazbin Hotel as the sole reason for
Helluva Boss being greenlit. On November 25, 2019, the
pilot was released on Medrano's YouTube channel. Medrano contributed her writing and animation skills to the episode. Writing production for more episodes began in December 2019, with 8 episodes ordered. The company
Horseless Cowboy assisted Medrano with voice work during the first season, with Richard Horvitz and Medrano voice directing. On October 31, 2020, the first episode of season 1 was released. In the episode, Rogers and Horvitz return as Blitzo and Moxxie, and while Lindbeck returns as Loona, she is replaced by Vivian Nixon as the voice of Millie. Baker was replaced by Bryce Pinkham as Stolas. Guest stars of the episode include Monsoon,
Mara Wilson, and
Maxwell Atoms. On January 31, 2021, the third episode of the series was
age-restricted by YouTube. In response, the entertainment site
Newgrounds offered to host an
uncensored version of the episode and promote it with "a front page banner", something which Medrano expressed interest in. The episode's age restriction was lifted the next day, and was later removed. In September 2021, Medrano spoke on a virtual stage at the Animation Exposé of the
Ottawa International Animation Festival about creating
Hazbin Hotel and
Helluva Boss. She was joined by Bryan Dimas, the associate producer of development at
Warner Bros. Animation and co-director of a group called LatinX in Animation. In February 2022, the official
Helluva Boss Twitter account stated that the season one finale would be out "soon" but that it was taking longer than expected, and noted that season two was in production. On June 3, 2022, the
Helluva Boss Twitter account released an update after the final episode of season 1 was delayed, and the series would instead be moving forward with season 2. The original season 1 finale was released a year later on June 24, 2023. The second season premiered on July 30, 2022. The series has included celebrities such as
Kesha,
Norman Reedus,
Mara Wilson,
Alex Brightman and others as guest stars. On March 27, 2023, the show was confirmed to be renewed for a third season, in active production. On May 25, 2023, Medrano stated that the series was planned to be "a very set 4 season story". On July 31, 2023, VivziePop posted titles for the upcoming episodes for season 2 on Twitter. On April 26, 2024, a spin-off short series of
Helluva Boss titled
Helluva Shorts was announced at LVLUP Expo, with the first short being released on the same day. On April 25, 2025, at Level Up EXPO 2025, it was announced that uncensored
Helluva Boss episodes of seasons 1 and 2 would be available on
Amazon Prime Video as well as being on YouTube which was released on September 10, 2025. It was also announced that new
Helluva Boss episodes for season 3 and 4 will be released on Amazon Prime first and then be uploaded to YouTube as normal for the series 45 days later. Alongside SpindleHorse,
Amazon MGM Studios will also help produce the series, with Medrano expressing that she was grateful to Prime Video for the opportunity and what it "means for the continued rise of indie animation.".
The A.V. Club also reported that Medrano and SpindleHorse would retain "full creative control and final cut on the series."
ComicBook.com later reported that Rochelle Diamante would be taking over the voice role of Beezlebub from
Kesha. The third season is set to be released in two halves, with the first premiering in late 2026, and the second half in 2027. == Soundtrack ==