The doctrine of signatures, also known as the doctrine of correspondences, is a biomedicinal theory of pseudoscience. It states that herbs or animals have physical or behavioral traits that mirror the ailment it can successfully treat. Theological justifications, such as that of botanist William Cole, were that God would want to show men what plants would be useful for. The doctrine of signatures has a debated origin. Many historians believe it begins with primitive thinking methods, while other historians believe it originated with Dioscorides and was popularized in the 16th and 17th centuries after Jakob Böhme coined the doctrine of signatures in his book The Signature of All Things.