Ramon Lopes started his professional career in the team of
Fluminense followed by a 1-year period of playing in
Cruzeiro. In early 2009 Ramon Lopes was transferred to Ukrainian side
Volyn Lutsk where he played in 78 games for 4,5 years, scoring 8 goals. In the summer of 2013, his contract expired and on 7 June 2013 Lopes was presented as a new player of Bulgarian side
Levski Sofia. He signed with the Bulgarians until 2015, but in August 2013 he again signed a contract, as a free agent, with FC Volyn. In June 2014, his transfer to
Vegalta Sendai of
J League was announced. On 29 July 2021, Lopes joined
Al-Fayha. On 19 May 2022, he scored the equalizer for Al-Fayha against
Al Hilal in the
2022 King Cup Final, which his club eventually won by 3–1 on penalties. On 15 September 2022, Lopes joined
Khor Fakkan. ==Club statistics==