Al-Mashat worked as an economist at the
International Monetary Fund in Washington DC from June 2001 until July 2005. and served on the Boards of the
Egyptian Exchange, Arab International Bank and the
Middle East Economic Association. She said of this role, "I think the experience I had was always to surprise people on the upside by being a capable, Arab woman." Al-Mashat became the first woman to hold the position and Egypt's youngest minister. In October 2018, Al-Mashat escorted US First Lady
Melania Trump on her visit to the
Giza Pyramids, saying that the visit conveyed the message of "Egypt's safety and security to the world." In January 2019, Al-Mashat announced that Egypt's Grand Museum will be launched in 2020 and will be run by the private sector as part of the government plan to step away from managing many ancient sites. Al-Mashat was one of six speakers at the World Tourism Forum in
Lucerne May 2019. In August 2023,
Abu Dhabi Islamic Bank Egypt (ADIB Egypt) named Al-Mashat as a member of its board of directors. Al-Mashat has spoken out about
gender equality and the importance of education, saying, "To all Egyptian girls, continue to invest in your education. The world is very competitive and what you know is what distinguishes you from anyone else." ==Awards and honours==