Benfica Guzzo was born in
São Paulo, Brazil, moving to Portugal before his tenth birthday and starting playing football with Associação Desportiva Flaviense. In 2008, the 13-year-old joined
S.L. Benfica's youth system. On 6 January 2013, still a junior, Guzzo made his professional debut with the latter's
reserve team, starting in a 1–1 home draw against
C.D. Santa Clara in the
Segunda Liga. He scored his first goal in the competition the following month, contributing to a 4–1 home win over
C.F. União. On 30 August 2014, Guzzo was loaned to second tier club
G.D. Chaves in a
season-long deal. The following 10 August, still owned by Benfica, he signed with
C.D. Tondela, but the loan was terminated on 28 January 2016. His maiden appearance in the
Primeira Liga with the latter took place on 14 August 2015, when he came on as a late
substitute for
Luís Machado in a 1–2 home loss to
Sporting CP.
Reus On 31 August 2016, Guzzo joined Spanish
Segunda División side
CF Reus Deportiu. His first match in the competition took place on 22 September, when he played 19 minutes in a 1–0 away win against
Real Oviedo. Guzzo returned to his adopted homeland on 16 August 2018, being loaned to
F.C. Famalicão for one year. He played 13 times as they
won promotion to the top flight as runners-up, and scored in a 3–1 defeat of former team Benfica B on 20 April 2019.
Vizela On 2 August 2019, Guzzo returned to Chaves as a
free agent and agreed to a two-year contract. In February 2021, however, he moved to
F.C. Vizela also in division two on a deal until June 2022. He scored six goals until the end of
that season in only 15 matches, helping the latter return to the top tier after 36 years. Guzzo put pen to paper to a one-year extension on 7 July 2021. He scored his first top-flight goal the following 22 January to equalise in a 3–2 win on his return to Tondela, adding another eight days later in a victory by the same score at home to
Vitória de Guimarães. On 7 July 2023, Vizela announced Guzzo's departure after his contract expired.
Goiás On 18 July 2023, Guzzo returned to his home country and signed a six-month deal with
Goiás Esporte Clube. He made his debut in the
Campeonato Brasileiro Série A on 13 August, playing the final half-hour of a 1–0 win at
América Futebol Clube (MG), and scored his only goal for
Armando Evangelista's men as the winner away to
Coritiba Foot Ball Club on 5 November; he was released at the end of his contract
following relegation.
Later career Guzzo returned for a third spell at Chaves in January 2024, signing a contract until the end of
the season. He scored against
Boavista FC (2–1 victory) and
F.C. Arouca (5–1 loss, also at home), in an eventual relegation as last. On 12 August 2024, Guzzo joined
Azerbaijan Premier League club
Neftçi PFK on a two-year deal. In June 2025, however, he left by mutual agreement. On 13 August 2025, Guzzo went back to Portugal and agreed to a two-year contract at second-tier
C.S. Marítimo. ==International career==