Slater's work constituted the first evidence for specific cortical pain response in premature infants from 25 weeks old. She measures the blood flow changes in the brain during clinically required blood tests using
near-infrared spectroscopy (NIRS) and compares it to the blood flow during non-painful tactile stimulation. She was the first to directly measure pain-specific neural activity in infants using
electroencephalography (EEG), during clinically required blood tests. This EEG measure was then developed by Slater and her research group into a general EEG template for measuring pain response in infants - a significant step towards using objective neuroimaging tools to evaluate pain experience in infants - which has been used to validate pain relief interventions for infants during clinical procedures. She is an advocate for neuroimaging tools for objective measurement of infant pain, and has demonstrated that brain activity could be more sensitive to pain responses in infants than other common assessment tools. As well as work directly within her research group, she is a collaborator on the developing Human Connectome Project (dHCP), a large-scale multi-centre project to develop the first developmental map of human brain connectivity between 20–44 weeks of age, that will include and link imaging, clinical, behavioural and genetic information. She has also been on the scientific organising committee for the International Symposium on Paediatric Pain. She is part of a collaboration to develop wearable
magnetoencephalography (MEG) scanners for children, described by
Physics World as one of the Top 10 Breakthroughs of the Year for 2019. One research study published in April 2015 involved infants, accompanied by their parents, being gently poked with a rod-like device while being scanned by
MRIs to measure and understand infant pain. This research suggested that "not only do babies experience pain but they may be more sensitive to it than adults" stated Slater. == Public engagement and media ==