Once widely considered to be generally unpredictable and aggressive,
P. brongersmai is gradually becoming more common among herpetoculturists. Formerly, many of the specimens in captivity were wild-caught adults from
Malaysia. These are known to be more aggressive than those from
Indonesia (
Sumatra), from which most of the wild-caught, wild-bred, and captive-bred stock are now descended. Captive-raised juveniles generally become mild-tempered, somewhat-predictable adults. This, combined with several new brightly colored captive bloodlines, is helping to boost the popularity of these much-maligned snakes among reptile hobbyists.
Python brongersmai is part of a commercial harvest for leather. There is evidence to suggest that there are clear indications of misdeclared, underreported and illegal trade involving tens of thousands of blood pythons, and there are questions whether this trade is sustainable. ==Taxonomy==