Jackson-Cohen landed a small role in the television series
Hollyoaks when he was 15, and he later appeared in the
ITV series
The Time of Your Life in 2007. and in the first episode of
Bonekickers. He also played Marcus in the short film
The Rooftopsmiths by Len Rowles with Natasha Freeman as Imogen and Philip Marden as Joel. In 2010, he played Damon in the romantic comedy film
Going the Distance starring
Drew Barrymore and
Justin Long. and a hitman in the action film
Faster, opposite
Dwayne Johnson. In 2011, he starred as
Prince William, Duke of Cambridge in a series of
Funny or Die videos with
Allison Williams as newlywed
Kate Middleton. Jackson-Cohen starred opposite
Cynthia Nixon in the miniseries
World Without End as Ralph. He appears in
Mr Selfridge with
Jeremy Piven where he plays the role of Roddy Temple. In 2013, Jackson-Cohen was cast as journalist
Jonathan Harker in the
NBC series
Dracula. In 2014, he was cast as Misha in the film adaptation of
Shamim Sarif's 2004 novel
Despite the Falling Snow. In March 2014, Jackson-Cohen was cast as
James, Duke of York in
ITV's four-part period drama miniseries
The Great Fire. It was announced in July 2014 that he would star opposite
Sarah Snook in the 2015
ABC convict miniseries
The Secret River, an adaptation of
Kate Grenville's 2005
novel of the same name. In 2015, Jackson-Cohen also starred in
The Healer as Alec Bailey. In the same year, Jackson-Cohen was cast as Lucas in
Emerald City, a television series that re-imagined the novel
The Wonderful Wizard of Oz by
L. Frank Baum. The series premiered in 2017 and was cancelled after one season. He then appeared in both seasons of the anthology web television series
The Haunting. Both seasons of the series,
The Haunting of Hill House and
The Haunting of Bly Manor, received strong critical praise. Jackson-Cohen next starred opposite
Elisabeth Moss in the
science fiction horror film
The Invisible Man, portraying
the titular role; the film was released in 2020 to positive reviews. He later stated that the press tour for the film was difficult because it began just three days after his father had died. In 2021, he appeared in the drama film
The Lost Daughter, directed by
Maggie Gyllenhaal. In 2022, he co-starred in the romantic
regency comedy ''
Mr. Malcolm's List, a film adaptation of the novel of the same name. In June 2021 it was announced that he would star in the upcoming Apple TV+ series Surface'' playing the character of James Ellis. The series premiered on 29 July 2022 to mixed critical reviews, though Jackson-Cohen's performance generally received critical praise. On 2 December 2022, the show was renewed for a second season. In June 2022, it was announced that Jackson-Cohen would star opposite
Jenna Coleman in the upcoming
Amazon Prime Video series
Wilderness, a television adaptation of B.E. Jones's novel of the same name, which began filming summer 2022 in Canada, the UK and the US and wrapped in October 2022. In February 2023, Jackson-Cohen was announced as the lead in the upcoming feature film
Jackdaw, written and directed by Jamie Childs. The film also stars his
Wilderness costar Jenna Coleman, and was shot in December 2022 through January 2023 in various locations across England's Northeast coast. The film had its world premiere at
Fantastic Fest on 22 September 2023. ==Personal life==