Full Length Plays •
Sixteen and Three Fourths (1975) •
Burles (Burlesque) (1977) •
Tribu (Tribe) (1979) •
Kontsabahan sa Tirarang (Conspiracy in Tirarang) (1979) •
Hiblang Abo (Strands of Gray) (1980) •
Sinakulo (1981) •
Sandaang Panaginip (A Hundred Dreams) (1981) •
Samperang Muta (Cheap Thrill) (1982) •
Madyik (Magic) (1983) •
Sigwa (Storm) (1984) •
Huling Istasyon (Last Station) (1983) •
Ang Hepe (The Chief) (1986) •
Awit ng Adarna (Song of the Adarna) (1987) •
Botong (1989) •
Tonyo (1990) •
Kalantiaw (1994) •
Bintao (1995) •
The Bomb! (2003)
One Act Plays •
Kumbersasyon (Conversation) (1980) •
May Isang Sundalo (There Is A Soldier) (1981) •
Nana (Mother) (1982) •
Huling Gabi sa Maragondon (Last Night at Maragondon) (1983) •
Punla ng Dekada (Seedlings of the Decade) (1984) •
Kaaway sa Sulod (Enemy Within) (1986) (with Rolando S. Dela Cruz) •
Mabuhay ang Pangulo (Long Live the President) (1987) (with Rolando S. Dela Cruz) •
Asawa (Spouse) (1987) (with Rolando S. Dela Cruz) •
Teodora (1993) •
Gregoria (1993) •
Dobol (Double) (1994) •
Watawat (Flag) (1999) •
White Love (2004) • ''Bertdey ni Guido (Guido's Birthday)'' (2007)
Two-act Documentary Play •
Sa Sariling Bayan (In One’s Own Land) (1988)
Translations and Adaptations •
Florente at Laura (Florente and Laura) (1988) •
Ang Napigil-Sanang-Paghahari ni Arturo Ui (
Bertolt Brecht's
The Resistible Rise of Arturo Ui) (1987) (with Joey Baquiran) •
Sutsot sa Dilim (Whistle in the Dark) (1985) •
Crimes of Passion (1985) •
Awit ng Adarna (Song of Adarna) (1984) •
Sa Kuko ng Liwanag (In the Claws of Neon Light) (1993) • "Isperekengkeng Isperekangkang" (A Comedy of Errors) (2005)
Children’s Plays •
Tiktipak-long (Grasshoppers) (1984) •
Si Pagong at si Matsing (The Turtle and the Monkey) (1984) (an opera with music by Lucrecia Kasilag) •
Ang Apoy ng mga Hayop (The Fire of the Animals) (1987) (music by Kasilag) •
Aguinaldo sa Niño (Gift for the Infant) (1987) •
Noong Unang Panahon (In the Beginning) (1988)
Screenplays •
Gabi na Kumander (It’s Night Commander) (1986) •
Kamagong (Mahagony) (1987) •
Anak ng Lupa (Child of the Earth) (1987)
Autobiography/Memoirs •
Personal: Mga Sanaysay Sa Lupalop Ng Gunita Teleplays •
Gabay Sa Pagsulat At Anim Na Dulang Pantelebisyon • ''Literature Eksena't Saknong'' (with Ligaya G. Tiamson Rubin)
Children's books •
Ang Pamilyang Ismid (The Family Ismid) co-published by Cacho Publishing House and Philippine Children’s Television Foundation •
Ang Patsotsay Na Iisa Ang Pakpak (The Patsotsay With Only One Wing) co-published by Cacho Publishing House and Philippine Children’s Television Foundation •
Ang Prinsipeng Ayaw Maligo (The Prince Who Hated Taking Baths) published by Cacho Publishing House. •
Ang Unang Baboy Sa Langit (The First Pig In Heaven) published by Cacho Publishing House. [1st Prize, Don Carlos Palanca Memorial Award for Literature, children's story, (Tagalog) 1990] •
Ayokong Pumasok Sa Paaralan (I Don't Want to Go to School) published by Cacho Publishing House. •
Dagat Sa Kama Ni Troy (The Sea in Troy's Bed) published by Cacho Publishing House. •
Gusto Kong Kumain Ng Pansit Ngayon (I Want to Eat Noodles Now) published by Cacho Publishing House. •
Kung Bakit Umuulan (Why It Rains) published by Cacho Publishing House. •
Nagsasabi Si Patpat (Patpat Says When) published by Cacho Publishing House. •
Nasaan Ang Tsinelas Ko? (Where Are My Slippers?) published by Cacho Publishing House. •
Okaka-okaka published by Cacho Publishing House. •
Sina Elephas At Estegodon Noon Unang Panahon (Elephas and Estegodon [Two Mammoths during Primeval Times]) published by Cacho Publishing House. •
Si Inggolok At Ang Planeta Pakaskas (Inggolok and the Planet Pakaskas) co-published by Cacho Publishing House and Philippine Children’s Television Foundation •
Si Paula Oink-oink published by Cacho Publishing House •
Sina Linggit Laban Kay Barakuda (Linggit against Barracuda [A retelling of a folktale]) co-published by Cacho Publishing House and Philippine Children’s Television Foundation •
Lumikha Ng Kuwento, Tula At Laruang Pambata (with
Virgilio Almario, Annaleah Habulan, Michelle Parazo Manual) • ''The Rene O. Villanueva Children's Reader'' (the author's own selection of his favorite stories, poems, plays and lyrics [English and Filipino]) published by Cacho Publishing House.
Song lyrics •
Batibot theme song (music by
Louie Ocampo) == Sources ==