Ribonucleoside-triphosphate reductase (EC 1.17.4.2, ribonucleotide reductase, 2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase) is an enzyme with systematic name 2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase. This enzyme catalyses the following chemical reaction2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O ribonucleoside triphosphate + thioredoxin