Brand names It is produced and marketed by
Warner Chilcott,
Sanofi-Aventis, and in Japan by
Takeda under the trade names Actonel, Atelvia, and Benet. It is also available in a preparation that includes a calcium carbonate supplement, as Actonel with Calcium.
Controversies In January 2006
P&G and its marketing partner
Sanofi-Aventis filed a
Lanham Act false claims lawsuit against rival drugmakers
Roche and
GlaxoSmithKline claiming false advertising about
Boniva. The manufacturers of Boniva, a rival bisphosphonate, were accused in the suit of causing a "serious public health risk" through misrepresentation of scientific findings. In a ruling on September 7, 2006, U.S. District Judge
Paul A. Crotty rejected P&G's attempted injunction. P&G was criticized for attempting to "preserve its market share by denigrating Boniva". Judge Crotty wrote that "Roche was clearly entitled to respond with its own data, provided that the data was truthfully and accurately presented". In 2006, P&G faced controversy over its handling of clinical research involving risedronate (News Reports and discussion). In common with other
bisphosphonate drugs, risedronate appears to be associated with the rare side effect
osteonecrosis of the jaw, often preceded by dental procedures inducing trauma to the bone. == References ==