On 17 May 1831, Lord Ebury was married to the Hon. Charlotte Arbuthnot Wellesley, eldest daughter of the diplomat
Henry Wellesley, 1st Baron Cowley (younger brother of
Arthur Wellesley, 1st Duke of Wellington). They had a London home at 29
Upper Grosvenor Street,
Mayfair. Together, they had five sons and two daughters including: •
Robert Wellesley Grosvenor, 2nd Baron Ebury (1834–1918), who married Hon. Emilie White, the second daughter of
Henry White, 1st Baron Annaly. • Hon. Thomas George Grosvenor (1842–1886), who married Sophia Williams, daughter of the American
missionary and
sinologist Samuel Wells Williams. • Hon.
Norman de l'Aigle Grosvenor (1845–1898), who represented
Chester in Parliament; he married
Caroline Stuart-Wortley, fourth daughter of
James Stuart-Wortley (third son of
James Stuart-Wortley-Mackenzie, 1st Baron Wharncliffe) and Hon.
Jane Lawley, in 1881. • Hon. Algernon Henry Grosvenor (1864–1907), who married Catherine Dorothea Mary Simeon, eldest daughter of
Sir John Simeon, 3rd Baronet and, his second wife, the former Hon. Catherine Dorothea Colville (sister of
Charles Colville, 1st Viscount Colville and daughter of Gen. Hon.
Sir Charles Colville), in 1887. • Hon. Richard Cecil Grosvenor (1848-1919), a barrister who married Jessie Amelia Clarke, a daughter of the Rev. Charles Clarke, in 1898. Lord Ebury died in November 1893, aged 92, and was succeeded in the barony by his eldest son
Robert. ==Arms==