In those days, appointments for such posts as federal Indian Agent were determined in great part by the political party in power, and the political affiliation of the agent. Neighbors was a
Democrat, so his services as Indian agent were terminated by the elections and subsequent national
Whig administration in September 1849. Neighbors stayed in public life however. Appointed as a Texas commissioner, he was sent by Texas Governor
Peter Hansborough Bell to organize
El Paso County in February and March 1850. He then attempted, without success, to organize counties in
New Mexico as a part of Texas, being opposed by Judge
Joab Houghton. He was a member of the
Fourth Texas Legislature, representing the Bexar and Medina District from 1851 to 1853. In 1852, he and state senator "Rip" Ford sponsored a resolution calling for Texas to negotiate with the federal government to settle the Indians in northern Texas. After urging from Secretary of War
Jefferson Davis to Governor Bell, the Texas legislature passed a law in 1854 granting twelve leagues of land for establishing Indian reservations. Neighbors became a
presidential elector in 1852, and following the election of
Franklin Pierce in 1853, was appointed supervising agent of the Indian service in Texas. In 1854, Neighbors and Capt.
Randolph B. Marcy, with an escort of forty soldiers, left
Fort Belknap in search of recommended sites for two Indian reservations to be established in 1855. Sites for the
Caddo,
Shawnee,
Anadarko,
Waco, Tawacano, and
Tonkawa, were located along the north side of the
Salt Fork Brazos River, south of what is now
Graham in
Young County. This area became the
Brazos Indian Reservation. The reservation's log buildings included the agent's house, an office, a
commissary store, a laborer's house, a school, a blacksmith, an interpreter's house, a privy, and a spring house; there were also several dome-shaped thatched native houses. File:Brazos Indian Reservation Texas Historical Marker.jpg|Brazos Indian Reservation Texas Historical Marker File:Brazos Indian Reservation School Texas Historical Marker.jpg|Brazos Indian Reservation School Texas Historical Marker File:Robert Neighbors Texas Historical Marker at Fort Belknap.jpg|Robert Neighbors Texas Historical Marker at Fort Belknap File:Tonkawa Scouts Texas Historical Marker at Fort Belknap.jpg|Tonkawa Scouts Texas Historical Marker at Fort Belknap File:Brazos Indian Reservation looking south towards the Brazos River.jpg|Brazos Indian Reservation looking south towards the Brazos River and the former site of the Anadarko and Caddo villages ==Camp Cooper and the Comanche Indian Reservation==