Cruz started as a host, together with his younger brother
Rayver, in the children's magazine show
5 and Up. Cruz was a member of the now defunct all-male dancing group Anim-E. The group, previously named Anime—in reference to the
Tagalog word "
anim" or "
six"—originally consisted six members namely: Rayver Cruz,
John Wayne Sace,
Emman Abeleda,
Sergio Garcia,
Mico Aytona, and
Mhyco Aquino. Rodjun joined the original members in 2005. In 2006, he was cast as Jigo in the
ABS-CBN TV series
Calla Lily. After a year, Cruz along with 14 other celebrity contestants joined the second season of
U Can Dance Version 2, where he met and started dating fellow Star Magic talent
Dianne Medina. Cruz with his dancing partner Lina Basas were named Grand Champion of U Can Dance Version 2 the following year, where he won the grand prize of 250,000 pesos. He also won another 250,000 pesos from the "
Merrygalo" segment of, the now defunct noontime variety show,
Wowowee. He made a guest appearance in the "
Mambabarang" episode of
Komiks Presents: Pedro Penduko at ang mga Engkantao in the same year. In 2008, Cruz was cast as Jake Perez in the
teen drama Lipgloss. Cruz left
Lipgloss after three seasons in 2009. He had minor roles in the
ABS-CBN shows
Tayong Dalawa and
May Bukas Pa. He also made guest appearances in
Maynila and
Midnight DJ. He played Calvin in
Magkaribal in 2010. He was also cast as Joaquin Buenaventura in
Juanita Banana. The same year, he left
ASAP XV and joined, the show's rival, P.O.5 in
TV5. ==Other ventures==