On August 30, 1685, with the guidance of her spiritual director and approval of her bishop, and with the assistance of her friends Gerolama Coluzzelli and Porzia Bacci, Venerini left her father's home and founded her first school in Viterbo for poor girls and young women, the first public school for girls in Italy. The objective of her school was "to give poor girls a complete Christian formation and to prepare them for life in society". It was quickly recognized by the civil and religious authorities, and she was recognized as a "born teacher". The teachers of Venerini's school faced public scrutiny because she was a woman and because her educational methods were unconventional, and at first, faced resistance from the clergy, who considered the teaching of the catechism their purview. As Butler states, "In these tasks she was undeterred by opposition, which sometimes resulted in arson and physical attacks on the teachers". Eventually, the clergy recognized that Venerini's school had a positive impact on the community and her fame spread outside of Viterbo. According to the
Vatican document published on the occasion of Venerini's
canonization, "Wherever a new school sprang up, in a short time a moral improvement could be noted in the youth". Venerini, on the invitation of
Cardinal Giovanni Barbarigo, the nephew of
Saint Gregorio Barbarigo, founded ten schools in
Montefiascone and the villages surrounding
Lake Bolsena between 1692 and 1694, and other schools were founded in
Lazio. Barbarigo did the fundraising and Venerini publicized the schools to families, trained the teachers, and organized the schools. It was during this time when Venerini befriended and became the confidante of
Saint Lucy Filippini, who she placed as head of the schools and who later organized the diocese's teachers into a separate religious congregation called the
Religious Teachers Filippini. Venerini tried to found a school in Rome, but failed. It took her six years, but she finally co-founded a school in central Rome, near the
Capitoline Hill, on December 8, 1713.
Pope Clement XI, accompanied by eight cardinals, visited the Roman school and observed their classes and instruction, on October 24, 1716, and approved their work. Because of the pope's support, Venerini founded more schools throughout Italy. Pope Clement told them, "Signora Rosa, you are doing that which we cannot do. We thank you very much, because with these schools you will sanctify Rome". She eventually opened over 40 schools. ==Death and legacy==