Jalosjos first started her political career when she was elected as member of the
Dapitan City Council from 2010 to 2013. She would go on to run for mayor of Dapitan, and won against Agapito Cardino (who only assumed office in January 2013 after the
Commission on Elections nullified her brother then-Mayor Dominador Jalosjos Jr.'s 2010 victory) in 2013, 2016, and in a hotly contested
2019 election against former Dipolog City mayor Evelyn Uy where disqualification cases were filed by the Jalosjos camp to question Uy's residency requirement. As her term as mayor was to end, she made her run as governor of Zamboanga del Norte where she faced Evelyn Uy again and four other candidates in the
2022 elections. From there, she went on to win the gubernatorial race, and take over the reins from the Uy family since the Jalosjos family's political defeat by the Uy family in 2013. In the
2025 local elections, she ran for mayor of Dipolog City facing
Roberto Uy, but was defeated. ==Personal life==