These are the populated places Route 5 passes through, as well as its main junctions with other National Roads. ;
Montevideo Department • after its junction with
Route 1, near the
Ángel S. Adami Airport, Route 102 connects with
Carrasco International Airport. ;
Canelones Department • Km. 33
Villa Felicidad • Km. 47
Canelones,
Route 11 Southeast to Atlántida & Northwest to San José de Mayo ;
Florida Department • Km. 75
Mendoza • Km. 94
Route 12 Southeast to
Minas &
Punta Ballena • Km. 98
Florida • Km. 143
Sarandí Grande ;
Durazno Department • Km. 183
Durazno,
Route 14 East to
Sarandí del Yí &
La Coronilla (Coast of Rocha), West to Trinidad &
Mercedes ;
Tacuarembó Department • Km. 249
Paso de los Toros • Km. 265 Route 20 to
Fray Bentos • Km. 390
Tacuarembó, Route 26 West & Southwest to
Paysandú, East & Southeast to Melo ;
Rivera Department • Km. 458 Route 30 Northwest to Artigas • Km. 496 Route 27 Southeast to
Vichadero and
Route 6 • Km. 501 Rivera - connects to Brazilian Federal Roads BR-158 and
BR-293. ==References==