The selection and deployment of the pictorial decoration was a saga that involved many of the premier painters of early 17th century Rome and Naples. The Deputation in charge of construction and decoration of the chapel, initially entrusted the pictorial decoration of the chapel to
Giuseppe Cesari, also called ''Cavalier d'Arpino''. The painter was popular in Rome under Pope
Clement VIII Aldobrandini and remained so under Pope
Paul V Borghese . A request was forwarded in 1616, and a contract was signed on March 7, 1618 But Cesari was slow to move to Naples, and the Deputation in 1620, revoked his contract and instead offered the position to
Guido Reni. Reni, after much haggling about payments, refused the assignment, and finally the commission was offered to painter
Fabrizio Santafede, who collaborated with
Battistello Caracciolo and the Bolognese pupil of Reni,
Francesco Gessi, to propose a design. The Deputation, however, was not satisfied with the plan. Soon after, Santafede died, and the team of Caracciolo and Gessi were fired. On December 2, 1628, they sent out requests for a new proposals, this time also including local Neapolitan painters. None of the submissions were satisfactory. In 1630, the deputation commissioned a sample painting from the painter
Domenico Zampieri (Domenichino), who like Reni, had been a pupil of
Carracci in Rome. They asked him to submit a painting depicting the
Martyrdom of San Gennaro (now in the museo del tesoro di San Gennaro). Pleased with the submission, he was hired in 1631. Domenichino completed the majority of the frescoes in the chapel. He painted the four pinnacles:
Pledge made by the Neapolitans in 1527,
Meeting of Saint Gennaro with Christ in the Heavenly Glory,
Virgin intercedes for Naples and
Patronage of Saints Gennaro, Agrippina and Agnello Abate. He also painted the
story of the life of San Gennaro in the three lunettes (1633) and in the arches. The four large altarpieces painted with oil on copper by
Domenichino represent: the
Beheading of Saint Januarius, the
Miracle of the infirm healed by the oil lamp, the
Infirm at the tomb of the Saint and
Resurrection of a dead man. Domenichino died suddenly on April 6, 1641. A few months later, he was replaced by another follower of Carracci who was then in Rome, the Emilian,
Giovanni Lanfranco. However, the Deputation on June 6, 1646, decided to ask the local painter
Massimo Stanzione, to complete the altarapiece of
Miracle of the Obsessed, left incomplete by Domenichino. Ultimately, Stanzione's submission was not acceptable, and they entrusted the work to
Jusepe de Ribera, who painted
San Gennaro emerges unscathed from the furnace of Cimitile. ==Architectural and Sculptural Contributions==