1983–2010: Academic and nonprofit career Newcombe began his career as a research assistant at the
Chelsea College of Science and Technology, where he worked on a project concerning secondary school policies towards smoking. From 1985 to 1987, he served as a research associate on the Wirral Misuse of Drugs Research Project team at the
University of Liverpool, where he explored the crisis of injected drugs, which was amplified by the AIDS pandemic. In 1987, he published his article "High Time for Harm Reduction" in
Druglink, which popularized the concept of
harm reduction. Newcombe next took research positions at the South Sefton District Health Authority and the
Mersey Region Health Authority. Between 1991 and 1993, he managed the Alcohol, Drugs & Crime Research Project at
The University of Manchester. In 2010, Newcombe relaunched the agency as 3D Research to pursue freelance research and advocacy. In his consulting, he worked with film and television agencies to appropriately portray drug use. This including working with
Benedict Cumberbatch for his role in the 2018 mini-series
Patrick Melrose. == Personal life ==