In
New England, anxious Mack
Mallard discourages his children Dax and Gwen from venturing beyond the pond, to the displeasure of his wife Pam. One day, the pond is visited by a flock of ducks who are migrating south to
Jamaica, which the family finds interesting, but Mack has no such interest. An upset Pam tells Mack that he must open his eyes to the world before he misses the opportunity. That night, Mack talks with his uncle Dan, who also does not want to leave the pond, but his loneliness and persuasion makes Mack reevaluate his stance and he decides to let his family migrate, with Uncle Dan joining them at Gwen's behest. As they begin their journey, the Mallards discover that they are flying in the opposite direction. During a thunderstorm, they take shelter in a swamp underneath a boardwalk where they encounter elderly
great blue heron Erin, who invites them to spend the night with her and her husband Harry in their shack. The family is afraid that Erin and Harry will have them for dinner. She says that back in the day Harry had a sharp eye and lightening reflexes for hunting. But now he is too old, and Erin brings the dinner back to the nest. Despite the herons' frightening countenance, Erin proves their good intentions by saving Dax and Gwen from a
catfish that almost swallowed them. The next day after leaving the swamp, the Mallards arrive in
New York City where Uncle Dan gets them in trouble with a flock of pigeons led by the pugnacious Chump. Pam defuses the situation and Chump introduces them to her friend Delroy, a
scarlet macaw from Jamaica who is caged by a cruel human chef that kidnapped him. Despite Dax's plea to help get the key, Mack and Pam infiltrate the restaurant where the chef works to acquire the key to Delroy's cage and free him; he guides them to Jamaica in return. While Gwen stops for a bathroom break, the group finds an entrance to a resort inhabited by
pekins. They enjoy the resort, until Dax discovers it is a duck farm, with the chef from earlier as its current client to purchase the pekins for food. Mack tells Dax to go back to Pam, but he instead alerts the pekins in order to help save them. He loses his wing feathers from being stepped on by the chef, rendering him flightless. The family, Delroy and the pekins escape the farm, and they later stop at a seaside motel to rest. Mack sternly scolds Dax for not listening to him and his reckless actions, worrying Pam and the others by his outburst and leaving Dax disappointed and upset. Later after the sun sets, the chef catches up and finds the birds via helicopter, capturing them except for Dax and Gwen who both manage to hide. Inside the helicopter, the chef plans to kill Mack and Pam first as revenge, putting them in a separate cage. Fearing the kids are lost, a despairing Pam begins regretting their migration until Mack regains her confidence, knowing she never gave up on anything, especially on him. Using a salsa dance they did back at the restaurant, and with Delroy and Uncle Dan's assistance, the caged Mack and Pam quietly sneak and try to reach a button to open the larger cage the others are trapped in, but the chef catches them in the act. A vengeful Delroy, aided by Uncle Dan and the pekins, pelt the chef with food until he is knocked unconscious, hitting the
trapdoor button as he, along with Mack and Pam, fall out. The chef is caught in the cargo net, and Mack and Pam continue to fall while still in their cage until Dax and Gwen come to save them; Dax repaired his wings with some of Delroy's shedded feathers that fell off when the chef kidnapped the birds. Mack and Dax reconcile, while Delroy, Uncle Dan and the pekins escape by breaking the cage mechanism. Now led by Dax, the birds arrive in Jamaica, where Delroy reunites with his family and friends while the Mallards catch up with the duck family who visited their pond earlier. Mack thanks Pam for helping him open his eyes to the world, and the birds dance together in celebration during sunset. The following spring, the Mallards meet a group of
Emperor penguins, whom they help bring back to the
South Pole as the Mallards set off on another adventure. ==Voice cast==