He married Constança Rodrigues, daughter of Rodrigo Lopes de Sequeiros (?) and wife, and had the following issue: • João Gonçalves da Câmara (d.
Funchal,
Madeira, 26 March 1501), married to Dona Mécia de Noronha, daughter of Dom João Henriques de Noronha (bastard son of
Alfonso, Count of Gijón and Noroña) and wife Beatriz, Lady de Mirabel and sister of Dom Garcia Henriques, and had issue, and also one son by an unknown mother • Rui Gonçalves da Câmara, 3rd Donatary Captain of
São Miguel Island, married to Maria de Bettencourt, natural daughter of Maciot de Bettencourt by Teguise, without issue, he had a son by one Maria Rodrigues and three more children by an unknown mother • Garcia Rodrigues da Câmara, married to Violante de Freitas, and had issue • Beatriz Gonçalves da Câmara, married to Diogo Cabral, and had issue • Isabel Gonçalves da Câmara, married to Diogo Afonso de Aguiar, o Velho (the Old), and had issue • Helena Gonçalves da Câmara, married to Martim Mendes de Vasconcelos, and had issue • Catarina Gonçalves da Câmara, married to Garcia Homem de Sousa ==Possible Jewish ancestry==