American football •
Sam Williams (defensive back) (born 1952), American football player •
Sam Williams (defensive lineman) (1931–2013), American professional football player of the 1960s •
Sam Williams (linebacker) (born 1980), American football linebacker •
Sam Williams (defensive end, born 1999), American football player
Basketball •
Sam Williams (basketball, born 1924) (1924–2012), American college basketball coach •
Sam Williams (basketball, born 1945), American basketball player for the Milwaukee Bucks •
Sam Williams (basketball, born 1959), American basketball player for the Golden State Warriors and Philadelphia 76ers
Other sports •
Sam Williams (soccer) (born 2005), American soccer player •
Sam Williams (rugby league) (born 1991), Australian rugby league footballer •
Sam Williams (footballer) (born 1987), English Association footballer •
Sam Williams (baseball) (1922–2007), American Negro leagues baseball player •
Sam Williams (rugby union) (1862–?), rugby union footballer ==Other==