Pre-draft Ebukam was not selected to participate in the 2017
NFL Combine, but he did participate in the
NFLPA Collegiate Bowl.
Los Angeles Rams 2017 The
Los Angeles Rams selected Ebukam in the fourth round with the 125th overall pick of the
2017 NFL draft. The Rams traded their fourth-round (141st overall) and sixth-round (197th overall) picks in the 2017 NFL Draft to the
New York Jets and received the fourth round pick (125th overall) used to draft Ebukam. Ebukam was the 17th linebacker drafted in 2017. Throughout training camp, Ebukam competed to be a backup outside linebacker against
Morgan Fox,
Ejuan Price,
Cory Littleton, and
Carlos Thompson. Head coach
Sean McVay named Ebukam a backup outside linebacker to start the regular season, behind
Robert Quinn and
Connor Barwin. He made his professional regular season debut in the Rams' season-opener against the
Indianapolis Colts and recorded three solo tackles in their 46–9 victory. On November 12, 2017, Ebukam recorded one solo tackle and forced the first fumble of his career during a sack in the Rams' 33–7 win against the
Houston Texans. Ebukam made his first career sack on Texans' quarterback
Tom Savage for a seven-yard loss and forced a fumble that was recovered by teammate
Tyrunn Walker in the third quarter. On December 3, 2017, Ebukam earned his first career start and collected a season-high five solo tackles in a 32–16 win at the
Arizona Cardinals in Week 13. He finished his rookie season in 2017 with 31 combined tackles (26 solo), two sacks, and a forced fumble in 16 games and two starts. The Los Angeles Rams finished the 2017 season first in the
NFC West with an 11–5 record and earned a playoff berth. On January 6, 2018, Ebukam appeared in his first career playoff game and made one tackle during the Rams' 26–13 loss against the
Atlanta Falcons in the
Wild Card Round.
2018 Ebukam entered training camp slated as a starting outside linebacker. Head coach Sean McVay named Ebukam and
Matt Longacre the starting outside linebackers to begin the regular season, alongside inside linebackers
Mark Barron and Cory Littleton. In Week 11 on
Monday Night Football, Ebukam scored two defensive touchdowns off turnovers (one fumble, one interception) and forced another interception in a
54–51 win over the
Kansas City Chiefs, earning him NFC Defensive Player of the Week honors. Ebukam finished the season with 40 tackles, one interception, and three forced fumbles. In the
Divisional Round against the
Dallas Cowboys, he recorded two tackles in a 30–22 win. In the
NFC Championship Game against the
New Orleans Saints, he recorded three tackles and a forced fumble in a tough 26–23 overtime victory. The Rams made it to
Super Bowl LIII where they played the
New England Patriots, but lost 3–13. Ebukam recorded four tackles in the Super Bowl.
2019 In 2019, Ebukam played in 16 games, with five starts. He recorded 48 tackles, four and a half sacks, one forced fumble, two fumble recoveries, and 4 passes defensed. Ebukam's first sack came late in the third quarter and resulted in a loss of one yard. His second sack occurred with just under ten minutes left in the fourth quarter on a second and goal play when he tackled quarterback
Kyler Murray eight yards behind the line of scrimmage, helping to force an Arizona field goal attempt. The kick was blocked, keeping the score at 18–7 Rams, which ended up as the final result. In the Rams wild-card round game against the
Seattle Seahawks, with just over seven minutes left in the fourth quarter and Los Angeles leading by ten points, the Rams punted the ball away on a fourth down. However, Ebukam forced returner
D. J. Reed to fumble the football, allowing the Rams to keep possession. The Los Angeles offense then scored a touchdown to take a 30–13 lead that proved insurmountable. The Rams went on to lose their next game against the
Green Bay Packers, ending their season.
San Francisco 49ers On March 19, 2021, Ebukam signed a two-year contract with the
San Francisco 49ers. In the 2021 season, Ebukam had 4.5 sacks, 38 total tackles, one pass defended, and one forced fumble in 17 appearances and 11 starts. In the 2022 season, Ebukam had five sacks, 36 total tackles, one pass defended, and one forced fumble in 15 appearances and starts.
Indianapolis Colts On March 17, 2023, Ebukam signed a three-year contract with the
Indianapolis Colts. In his first season with the Colts, Ebukam led the team with a career-high 9.5 sacks, and also set career-highs with 57 tackles and three forced fumbles. On July 29, 2024, it was announced that Ebukam would be out for the season after suffering a
torn Achilles tendon. Ebukam returned from his injury and had two sacks, 33 tackles, and one fumble recovery in 14 games in the 2025 season.
Atlanta Falcons On March 16, 2026, Ebukam signed a one-year, $2.7 million contract with the
Atlanta Falcons. ==NFL career statistics==