It was built in 1645–50 with funds given by
Olimpia Aldobrandini Pamphili, who (like St Francis) had roots in
Calabria. It was designed by Giovanni Pietro Morandi, given to the Minim Friars, and became the national church of the Calabrians. The monastery was refurbished under Father Francesco Zavaroni di Montalto, General of the order, and using as an architect Luigi Berettoni. The late
Baroque high altar was made by Giovanni Antonio de Rossi c. 1655 (who is also credited with the church's wooden
tabernacle, set into a sculptured entrance of a military pavilion). No new
bell tower was built for the church - instead the 12th century
Torre dei Margani was used, preserving its medieval coat-of-arms on the tower has been preserved. However, the church as a whole was not consecrated until 10 July 1728, by
Pope Benedict XIII. The lower part of the façade was refinished in plaster in the 18th century, and the whole church was then restored in 1826 by
Pope Leo XII. The recent titular
cardinal-deacon of the church, from 21 October 2003 until his death was
Renato Martino. ==Chapels==