When the
Houston Comets folded in 2008, Lyttle was selected first in the
dispersal draft by the
Atlanta Dream. She played the
power forward position for the
Phoenix Mercury in the
WNBA. Over her career, Lyttle has scored over 1,500 points, collected over 1,000 rebounds, and had 200 assists, 242 steals, and 96 blocks through six seasons. She was the fifth overall draft pick in the
2005 WNBA draft out of
Houston. In 2010, Lyttle had career highs in points and rebounds with 27 and 20, respectively. She was hospitalized for a number of days in 2010 after being knocked unconscious for a little over a minute by an incidental elbow during a game. Lyttle recovered and played 13 days later. On February 1, 2018, Lyttle signed with the
Phoenix Mercury after spending the previous nine seasons with the
Atlanta Dream. However, her season ended early when she tore her ACL on June 30, 2018. In September 2019, Little announced her retirement after 15 WNBA seasons. ==Euroleague career==