2009–10: Major singles debut, Top 100 & First ATP title in doubles González qualified at the
2009 Wimbledon Championships to make his Grand Slam debut. He lost his first round main draw match in Wimbledon against Israeli
Dudi Sela. He also made his Grand Slam debut in qualifications in singles at the
2009 Australian Open. He made his top 100 doubles debut on 12 October 2009. He won his first ATP title at the
2010 Serbia Open partnering American
Travis Rettenmaier.
2011–14: Eight doubles titles, top 25 debut In April 2011, partnering with American
Scott Lipsky, he won the
ATP World Tour 500 title of the
Barcelona Open. They defeated the
Bryan brothers 5–7, 6–2, [12–10], breaking their 10-match winning streak. They also defeated doubles teams
Jürgen Melzer &
Nenad Zimonjić 6–3, 6–2, and
Max Mirnyi &
Daniel Nestor 7–6, 6–4. He reached the top 25 on 30 January 2012. He won a total of seven titles with Lipsky between 2011 and 2014.
2017: French Open doubles final In June 2017, he reached his first Grand Slam final partnering
Donald Young of the US at the French Open.
2021: Fifteenth title In 2021, González and his then partner
Marcelo Demoliner took the first dose of a
COVID-19 vaccine at the
2021 Serbia Open. During the grass season, he won his fourteenth ATP title at
Stuttgart Open defeating Uruguayan
Ariel Behar and
Gonzalo Escobar from Ecuador with Demoliner. In September, González won his fifteenth ATP doubles title at the
2021 Astana Open partnering
Andrés Molteni. In November he won the
2021 Stockholm Open his sixteenth title also with Molteni.
2022–23: 350th ATP career win, First two Masters, World No. 7 In 2022, he won two more clay titles with Molteni at the
2022 Córdoba Open and
2022 Argentina Open. He made his maiden Masters final at the
2022 BNP Paribas Open in Indian Wells with
Édouard Roger-Vasselin using a protected ranking after defeating reigning US Open Champions and 2nd seeded pair of
Joe Salisbury and
Rajeev Ram. They lost in the final to American duo Isner/Sock. As a result, he reached a new doubles career-high of No. 22 on 21 March 2022. Unseeded he reached his second Masters final at the
2023 Miami Open with Édouard Roger-Vasselin after defeating Americans
Jackson Withrow and
Nathaniel Lammons, recording his 350th ATP career win. He won his first Masters title and 20th overall defeating
Nicolas Mahut and
Austin Krajicek. He made his debut in the top 20 on 24 April 2023. Following the
2023 French Open, he made his debut in the top 15 on 12 June 2023. In August, he won the
2023 Los Cabos Open, his twenty-first title also with
Édouard Roger-Vasselin. In October, he won the
2023 Basel Open, his twenty-second title. With reaching the final at the
2023 Rolex Paris Masters, his second at this level for the season, he entered the top 10 in the rankings. He won the title with Roger-Vasselin defeating Bopanna/Ebden. On 2 November, Gonzalez qualified with Roger-Vasselin for the
2023 ATP Finals for the first time in his career and became the first Mexican to qualify for the year-end event since
Jorge Lozano in 1989. They reached the semifinals after winning their round robin matches against M. Gonzalez/A. Molteni and I. Dodig/A. Krajicek.
2024: Historic mixed doubles final at Wimbledon At the
2024 Wimbledon Championships, he reached his fourth career final in mixed doubles with compatriot
Giuliana Olmos. They became the first Mexican duo to reach the mixed doubles final. Gonzalez became the first Mexican man since
Raúl Ramírez in 1973 to reach the final of the same event at the All England Club. They lost in the final in straight sets to
Jan Zieliński and
Hsieh Su-wei. ==Significant finals==