The present structure is the fourth church built on the same site to house the Dominican congregation in Santiago. Earthquakes in 1595,
1647, and
1730 destroyed the early churches. The fourth church began to be constructed in 1747 under the design of architect Juan de los Santos Vasconcellos.
Joaquín Toesca worked on its construction between 1795 and 1796. The first occurred in 1895 == Architecture ==