The team was established in 1945 as Queliteros de Hermosillo (). In 1947, the Queliteros won their first championship in the Liga de la Costa del Pacífico (Pacific Coast League), the competition that preceded the
Mexican Pacific League. The club changed its name to the current Naranjeros in the 50s and won the Pacific Coast League back to back in the 1955–56 and 1956–57 seasons. The Naranjeros played in the Estadio de la Casa del Pueblo that was later renamed to Estadio Fernando M. Ortiz. Hermosillo repeated the feat of winning the league championship twice in a row in the 1960–61 and 1961–62 seasons, both times under manager Virgilio Arteaga. They won the league again in the 1963–64 season. During these years, legendary player
Héctor Espino was part of the team. The Naranjeros won the 1970–71 season and therefore became the first Pacific League team to represent Mexico in the
1971 Caribbean Series. In 1972 the team moved to the
Estadio Coloso del Choyal. They won the 1974–75 and 1975–76 seasons back to back and participated in the
1976 Caribbean Series. The Naranjeros' victory at the 1976 Caribbean Series in Santo Domingo was the first ever by a Mexican team. The club was managed by
Benjamín "Cananea" Reyes and included players such as
Héctor Espino (1B),
Sergio "Kalimán" Robles (C),
Celerino Sánchez (3B),
Elliot Willis (2B),
Arnoldo de Hoyos (CF),
George Brunett (P) and
Jerry Hairston Sr. (LF). Again under Cananea Reyes, the Naranjeros won the 1979–80 season. With
Tom Harmon as manager, Hermosillo won the 1981–82, 1989–90 and 1991–92 seasons. In the 1993–94, 1994–95 and 2000–01 seasons, the Naranjeros won the Mexican Pacific League, led by manager
Derek Bryant. Under
Lorenzo Bundy, Hermosillo won the 2006–07 season and were champions again in the 2009–10 season with
Homar Rojas as manager. In 2013, the Naranjeros moved to
Estadio Sonora. During that season, the team won its seventeenth league title and the
2014 Caribbean Series with
Matías Carrillo as manager defeating
Indios de Mayagüez 7–1 in the final. Ten years later, the Naranjeros won its eighteenth LMP championship in the
2023–24 under manager
Juan Gabriel Castro, sweeping the
Venados de Mazatlán 4–0 in the championship series. The team represented Mexico at the
2024 Caribbean Series played in Miami. The Naranjeros finished sixth with a 2–4 record, managing to defeat
Tigres del Licey and
Gigantes de Rivas, but losing their other four games, thus, being eliminated in the first round of the tournament. ==Stadium==