Sarah Hussey Earle was an abolitionist, American Quaker, and women's rights activist. She was born in Nantucket, Massachusetts and married John Milton Earle on June 6, 1821, before moving to Worcester, Massachusetts. She founded the Worcester Ladies Anti-Slavery Sewing Circle and served as its president in 1839. She assisted and served on committees of the Worcester County Anti-Slavery Society, South Division from 1841 and was the first woman to serve as one of the vice presidents of the South Division before her death in 1858. Additionally, Earle coordinated Worcester anti-slavery fairs from 1848 and organized fundraising for the American Anti-Slavery Society, eventually sending donations to Maria Weston Chapman. She founded and was president of the Worcester City Anti-Slavery Society, in addition to organizing lectures for the organization. She gave the opening address to the first National Women's Rights Convention, which was held in Worcester, Massachusetts, in 1850, and was elected president of the 1854 New England Women's Rights Convention in Boston.