Howe opened the Ladies' Deposit Company sometime before April 1879 as a
savings bank that accepted deposits only from unmarried women. She told depositors that the bank worked with a
Quaker charity that wanted to help women of modest means. She promised a very high interest rate on the deposits, initially described as two percent per week, which was later adjusted to eight percent per month. In fact there was no such charity and Howe relied on new deposits to pay the interest on older ones. Howe did not advertise the bank, but was able to attract $500,000 () in deposits from about 1200 women in cities as far away as Chicago and Washington by relying on
referrals from her depositors. In September 1880, the
Boston Daily Advertiser began publishing articles attacking the Ladies' Deposit as a swindle, which led to a
run on the bank by its depositors. By October the scheme had collapsed and Howe was charged with multiple counts of fraud. She was convicted and served three years in prison. ==Later life==