In 1988, Assadourian entered politics as the Liberal candidate in the riding of
Don Valley North. He won the Liberal nomination over rival
Sarmite Bulte. During the campaign debate he said that he wanted, "honest and open government, for a change." The New Democratic Party candidate,
Anton Kuerti reminded him that the Tories were elected in 1984 criticising the Liberals on the same issue. Assadourian stated that he was staunchly against abortion which was a hot button issue during the campaign. In 1997, Assadourian moved seats to
Brampton Centre. In 2003, he served as
Parliamentary Secretary to the
Minister of Citizenship and Immigration. He did not run in the
2004 election. Assadourian ran in the 2010 Richmond Hill Municipal Elections in Ward 3. He placed fifth out of seven candidates. He ran again
in 2022 in Ward 5, placing eighth out of 10 candidates. ==After politics==