Jaison Pazhayattu wrote the film's script after being inspired by a real life incident in Chennai, where people had allegedly experienced a supernatural presence. He cast
Ineya in the leading female role, opposite a Malayalam actor
Felix Kuruvilla who plays the ghost Stephen in the film, while
Rahman also accepted to work on the film after being convinced by Jaison's Pazhayattu narration. Malayalam actor Nikhil Mohan, Kannada actor Akash and
Swathi Deekshith, who had earlier appeared in
Ram Gopal Varma's horror film
Ice Cream (2014) were also signed. The film was also one of the final projects of cinematographer Anandakuttan, who was replaced by I. Francis after his death.
Sathura Adi 3500 was shot extensively in Bengaluru, Chalakudy, ECR and other interior parts of Chennai during late 2016. The success of
Dhuruvangal Pathinaaru (2016) starring Rahman prompted producers of his delayed ventures to publicise and release their films to make most of the actor's renaissance at the box office. Subsequently, after the release of
Pagadi Aattam in February 2017 and
Oru Mugathirai in March 2017, the makers of
Sathura Adi 5000 chose to promote Rahman as one of the film's main characters despite his relatively small role. During the film's audio launch in July 2017, veteran director
K. Bhagyaraj criticised actress
Ineya for failing to attend the event. Bhagyaraj called for producers to think twice before casting her, and stated that she was not in the top bracket of actresses. Ineya later played down Bhagyaraj's comments and stated she was recuperating from an ankle injury. She also revealed that the team had merely sent her a
WhatsApp message telling her to attend rather than providing a formal invitation. ==Soundtrack==