The museum was called the North Western Museum of Science and Industry when it opened in 1969 in temporary premises on Grosvenor Street in
Chorlton-on-Medlock. It had close ties with the
University of Manchester Institute of Science & Technology, having mostly grown out of the Department of History of Science & Technology, and UMIST's
Richard L. Hills was the museum's first lecturer in charge. In 1978,
Greater Manchester Council purchased the earliest part of the former
Liverpool Road station from
British Rail, which had been closed in 1975. The council paid the nominal sum of £1 for the site. The museum opened at this site on 15 September 1983 and later expanded to include the whole of the former station. Since 2007 the museum has organised an annual
science festival in Manchester. In 2014, Sally MacDonald became the director. MacDonald left her role as head of collections at
University College London and succeeded Jean Franczyk as director. In 2021, the permanent closure of the Air and Space Hall was announced. Objects were returned to their original owners, and those owned by the museum displayed in future exhibits. == Exhibitions ==