Puig's second government saw a number of cabinet changes during its tenure: • On 27 August 2021, second vice president and minister of Housing and Bioclimatic Architecture,
Rubén Martínez Dalmau, announced his incoming resignation and farewell from politics following a number of disagreements with his party, Podem. The resignation was effective from 10 September, when Dalmau was replaced in both his posts by
Héctor Illueca. • On 14 May 2022, the cabinet saw an extensive reshuffle.
Arcadi España replaced Vicent Soler at the helm of the Finance and Economic Model department, in turn being replaced as Territorial Policy, Public Works and Mobility minister by
Rebeca Torró.
Vicent Marzà vacated the Education, Culture and Sports ministry, who was assumed by
Raquel Tamarit, whereas the Universal Healthcare and Public Health post saw Ana Barceló being replaced by Miguel Mínguez. Carolina Pascual was replaced as Minister of Innovation, Universities, Science and Digital Society by Josefina Bueno. • On 21 June 2022, vice president
Mónica Oltra resigned from all her government positions after the
High Court of Justice of Valencia accused her and her ministry of negligence in the protection of a minor who was allegedly abused by her ex-husband, as well as an alleged concealment of the crimes. She was replaced in her government posts by Aitana Mas on 29 June. • On 25 October 2022, Mireia Mollà was removed as Minister of Agriculture, Rural Development, Climate Emergency and Ecological Transition by request of Aitana Mas, unveiling an internal crisis within their party,
Valencian People's Initiative (IdPV). She was replaced in her post by
Isaura Navarro the next day. ==Council of Government==