Segnature is a traditional folk healing practice from Italy. It uses hand gestures, secret prayers, and signs. It is used to cure sickness, remove curses such as the evil eye, protect people, and influence natural forces such as the weather. Segnature has persisted through Italian history because its roots are in a cultural heritage that blends pre-Christian folk beliefs with Catholic ritual elements. By adapting to social changes, it has become a vital part of local healing traditions. Healers who use Segnature are known as Segnatori. The practice involves drawing signs on the body or objects while reciting prayers or words of power. These are often passed down through family or community lineages. Segnature has been and continues to be practised in rural areas. In recent years, it has seen a resurgence through social media, where practitioners share knowledge with one another. Recent academic research has begun to recognize Segnature as a form of indigenous Italian shamanism. It is a folk tradition that blends cultural identity, healing, and spirituality. The word "segnature," which translates as "signs" or "marks," emphasises the importance of ritual gestures in the practice. Often misinterpreted and viewed as a type of witchcraft, Segnature has an important place in Italian culture and is centred on protection and healing. The names for the practice can vary by region, for example, "Janare" or "Masca."