Boston Celtics (2017–2021) Following the close of his redshirt junior season, Ojeleye entered his name for the
2017 NBA draft but did not hire an agent, leaving open the possibility of a return to the Mustangs. Ojeleye was invited to the 2017
NBA Draft Combine, one of 67 participants. After some promising performances he announced that he would commit to the draft, ending his college career. Ojeleye was chosen by the
Boston Celtics in the second round with the 37th overall pick. Ojeleye made his professional debut on October 17, 2017, in a 102–99 loss to the
Cleveland Cavaliers. During the regular season, he averaged 2.7 points per game and shot 34.6 percent from the field, but emerged as a defensive presence. He started in Game 5 of the playoff series versus the
Milwaukee Bucks and held
Giannis Antetokounmpo to 16 points.
Milwaukee Bucks (2021–2022) On August 6, 2021, Ojeleye signed with the
Milwaukee Bucks on a one-year, veteran's minimum contract.
Los Angeles Clippers (2022) On February 10, 2022, Ojeleye was traded to the
Los Angeles Clippers as part of a four-team trade. On March 26, he was waived.
Virtus Bologna (2022–2023) On July 28, 2022, Ojeleye signed a two-year deal with
Virtus Bologna of the Italian
Lega Basket Serie A (LBA) and the
EuroLeague. On 29 September 2022, after having ousted
Olimpia Milano in the semifinals, Virtus won its
third Supercup, defeating 72–69
Banco di Sardegna Sassari and achieving a back-to-back, following the 2021 trophy. Ojeleye was nominated MVP of the competition. However, despite good premises Virtus ended the
EuroLeague season at the 14th place, thus it did not qualify for the playoffs. Moreover, the team was defeated in the
Italian Basketball Cup final by
Brescia. In June, after having ousted 3–0 both Brindisi and Tortona, Virtus was defeated 4–3 by Olimpia Milan in the national finals, following a series which was widely regarded among the best in the latest years of Italian basketball.
Valencia (2023–2025) On July 1, 2023, Ojeleye's contract with Bologna was bought out by Spanish club
Valencia for a sum of $300,000.
Crvena zvezda (2025–present) On June 30, 2025, Ojeleye signed with
Crvena zvezda of the
ABA League. ==Career statistics ==