MarketMilbemycin oxime/lufenuron
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Milbemycin oxime/lufenuron

The combination milbemycin oxime/lufenuron is a parasite control drug in which the active ingredient, milbemycin oxime, eliminates worms, while a second active ingredient, lufenuron, arrests the development of eggs and larvae, preventing them from maturing and continuing the infestation of an animal. This combination is registered for animal use only. To achieve efficacy, the treatment is administered once monthly, together with food, in a dosage suitable for the weight of the affected animal. The usual ratio is 500 μg milbemycin oxime and 10 mg lufenuron/kg body weight. Novartis indicates the proper dosage by color-coding the packages.

Side effects
Milbemycin oxime/lufenuron can lead to a negative physical response in some animals, most severely those that have heartworm disease or weigh under 2 lbs. It is recommended that all dogs be tested for heartworm prior to taking the medication to minimize this risk. Serious side effects may include lethargy, weakness, stumbling, seizures, coma, excessive drooling, and wide dilated pupils. Less serious side effects are an upset stomach or loss of appetite, various skin irritations, and mood changes. ==References==
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