After graduating in 1918, Muir-Wood researched the shelled marine animals known as
brachiopods at University College. In 1919, she took a part-time job at the London
Natural History Museum (then the Natural History department of the
British Museum), and was appointed head of the brachiopod collection in 1920 . She rose through the ranks of geology assistants to become, in 1955, the first woman appointed Deputy Keeper of Palaeontology for the museum. She officially retired in 1961, but she continued to do some work at the museum for another four years. Muir-Wood was an authority on brachiopods, especially fossil types found in the British isles, the Middle East, India, and Malaysia. For three years during the Second World War she worked with the Admiralty in Bath, but maintained her research interests through fossil collecting in the area. She also worked on classification system for
Mesozoic species and genera in the 1930s, which was considered pioneering. She published extensively on brachiopods, and travelled to the US twice to work on a study of the Productoidea with
G. Arthur Cooper of the
Smithsonian Institution. When the work was published in 1960 as “Morphology, classification and life habits of the Productoidea (Brachiopoda)”, it “was quickly recognized by brachiopod workers as being one of the greatest contributions to the studv of the phylum.” Mui-Wood was then invited to co-author the section on brachiopods in the 1965 survey
Treatise on Invertebrate Paleontology. Muir-Wood was awarded the Lyell Fund by the
Geological Society of London in 1930 and the
Lyell Medal in 1958. On her retirement in 1965, she was awarded the
Order of the British Empire for her services to the museum. Muir-Wood died of a stroke in Hampstead in 1968, aged 72. ==Selected publications==