In the 1960s, Di Stefano attended the
Silvio d'Amico National Academy of Dramatic Arts and began his acting career on stage and on television. In 1970, he contributed voice acting work to
Pino Zac's animated feature film based on
Italo Calvino's
The Nonexistent Knight, while the following year he played the role of Jack Reedy in the television miniseries
E le stelle stanno a guardare. During the same period he also began a career as a voice dubbing artist and became well known for giving his voice to actors like
John Malkovich,
Jeff Bridges,
Alan Rickman,
William Hurt and especially
Hugh Laurie as
Gregory House in the first six seasons of
House and
Jonathan Frakes as
William Riker in
Star Trek: The Next Generation. Di Stefano was also noted for dubbing
Christopher Lambert,
Christopher Reeve,
Alec Baldwin,
Jeff Goldblum and
Robert Englund in some of their performances. In his animated roles, he gave his voice to characters in several Italian dubbed anime productions. Additionally, he voiced Johnny Bravo in the Italian dub of
Johnny Bravo as well as Barkis Bittern in the Italian dub of
Corpse Bride and Dr. Cockroach in the Italian dub of
Monsters vs Aliens. ==Death==