'' bees
Rhododendron species and other plants in the family
Ericaceae produce
grayanotoxins. Honey made from the
nectar contains
pollen from these plants as well as the grayanotoxins. Due to its reddish color, it is sometimes called
rose of the forest honey. Mad honey is produced in specific world regions, notably the
Black Sea Region of Turkey and
Nepal. Small-scale producers of mad honey typically harvest honey from a small area or single
hive, producing a honey containing a significant concentration of grayanotoxins. In contrast, large-scale honey production often mixes honey gathered from different locations, diluting the concentration of any contaminated honey. A
Caucasus beekeeper noted in a 1929 article in
Bee World that the potency of the honey could vary across a single honeycomb and that the most dangerous mad honey was produced at high elevations during dry spells. Beekeepers in the
Kaçkar Mountains have produced mad honey for centuries. In southern Asia,
Apis laboriosa nests are found mostly in the
Hindu Kush Himalayan region.
Honey gathering In central Nepal and northern India, the
Gurung people have traditionally
gathered the honey for centuries, scaling cliffsides to reach the hives. Residents collect the honey twice a year, once in late spring and once in the late fall. The honey hunters use rope ladders with wooden rungs to access the nests and set fires underneath to smoke out the bees. A specialist with the
International Centre for Integrated Mountain Development reported in 2022 that there had been a decrease both in the number of cliffs that host bees and in the number of colonies each cliff supports. Recommendations for sustainable honey harvesting include leaving half of the newly formed combs undisturbed and only harvesting portions of the combs.
In other regions United States Mad honey is rarely produced in the United States. According to
Texas A&M professor Vaughn Bryant, an expert on honey, mad honey is produced in the
Appalachian Mountains in the Eastern U.S. when a late cold snap kills most flowers but not rhododendrons. Honeys produced from
mountain laurel (
Kalmia latifolia) and
sheep laurel (
Kalmia angustifolia) also contain grayanotoxins and are potentially deadly if large quantities are eaten.
Europe In Europe, honey containing grayanotoxins is produced from
Rhododendron ferrugineum, which occurs in the
Alps and
Pyrenees. However, no grayanane intoxication cases have been reported for honeys from the
European Union. ==Physiological effects==