Polydactylus sextarius is found where there are sandy and muddy bottoms on the continental shelf and it appears to favour depths of . This carnivorous species has its diet dominated by shrimps of less than length and
amphipods but it has also been recorded feeding on crabs,
mysids, fishes and
polychaetes. Sampling of the population in the
Bay of Bengal off India found that a large proportion of the fish are hermaphrodites and that these fell within the range of standard length of , with a smaller proportion of females with standard lengths of between . The hermaphrodites with comparatively large
testes were counted as mature males and these measured standard length) while the fish with granulated ova of diameter were considered to be mature females and these fell within the standard length range of . The species undergoes a
protandrous sex change starting as juveniles, becoming hermaphrodites and ending as females progression. They first reach sexual maturity as hermaphrodites which function as males and there is no evidence which suggests that females develop directly from juveniles. ==Fisheries==