Main •
Katherine McNamara as
Clary Fairchild, a Shadowhunter raised among mundanes (humans) who finds out her true heritage on her 18th birthday. She is the daughter of Jocelyn Fairchild and Valentine Morgenstern. •
Dominic Sherwood as
Jace Herondale, a charming and narcissistic playboy Shadowhunter who falls in love with Clary and is the adoptive brother of Alec, Isabelle and Max Lightwood •
Alberto Rosende as
Simon Lewis, Clary's childhood best friend who gets involved in the Shadow World and later becomes a vampire •
Matthew Daddario as
Alec Lightwood, a serious and no-nonsense Shadowhunter, the older brother of Isabelle and Max and the adoptive brother and Parabatai of Jace •
Emeraude Toubia as
Isabelle Lightwood, a seductive and charismatic Shadowhunter who is the younger sister of Alec, the older sister of Max and the adoptive sister of Jace •
Isaiah Mustafa as
Luke Garroway, a former Shadowhunter turned werewolf and NYPD police officer •
Harry Shum Jr. as
Magnus Bane, a very powerful, intelligent and wise warlock who is the former High Warlock of Brooklyn •
Alisha Wainwright as
Maia Roberts (season 3; recurring season 2), a mundane turned werewolf, a member of Luke's pack, and the bartender at the Hunter's Moon
Recurring Introduced in season one •
Alan van Sprang as
Valentine Morgenstern (seasons 1–2; guest season 3), a rogue Shadowhunter and the leader of the Circle •
Maxim Roy as
Jocelyn Fairchild (seasons 1–2; guest season 3), Clary's warm and protective mother and Valentine's ex-wife, who is a former member of the Circle • Vanessa Matsui as Dorothea Rollins (seasons 1–2), a younger warlock who is Jocelyn's assistant at the shop Jocelyn owns and a sister figure to Clary •
Jon Cor as
Hodge Starkweather (season 1; guest season 2), a former Circle member and the weapons trainer at the New York Institute •
David Castro as
Raphael Santiago, a catholic vampire who is Camille's former right-hand man and the former leader of the Brooklyn vampire clan •
Jade Hassouné as Meliorn, a Seelie Knight loyal to the Seelie Queen and Isabelle's ex-lover • Kaitlyn Leeb as
Camille Belcourt (season 1; guest season 2), the former leader of the Brooklyn vampire clan and Magnus' ex-girlfriend •
Christina Cox as Elaine Lewis, Simon and Rebecca's widowed mother •
Nicola Correia-Damude as
Maryse Lightwood, the former head of the New York Institute and former member of the Circle • Paulino Nunes as
Robert Lightwood (seasons 1–2; guest season 3), a former member of the Circle • Jack Fulton as
Max Lightwood (seasons 1–2; guest season 3), Alec and Isabelle's precocious younger brother and Jace's adoptive brother who is eager to become a Shadowhunter •
Holly Deveaux as Rebecca Lewis (seasons 2–3; guest season 1), Simon's older sister •
Stephanie Bennett as Lydia Branwell (seasons 1–2), a member of the Clave who temporarily takes over the New York Institute •
Raymond Ablack as Raj (seasons 1–2; guest season 3), a Shadowhunter who often enforces the orders of the head of the New York Institute •
Mimi Kuzyk as
Imogen Herondale (seasons 2–3; guest season 1), the former Inquisitor of the Clave • Joel Labelle as Alaric Rodriguez (seasons 1–2), a werewolf who is Luke's NYPD partner •
Jordan Hudyma as Blackwell (season 1) •
Shailene Garnett as
Maureen Brown (season 1), Clary and Simon's friend and Simon's bandmate •
Stephen R. Hart as Brother Jeremiah (seasons 1–2), one of the Silent Brothers
Introduced in season two •
Nick Sagar as Victor Aldertree (season 2; guest season 3), a Clave diplomat who takes over the Institute and leads the manhunt on Jace •
Lisa Berry as Sister Cleophas Garroway (season 2; guest season 3), a former member of the Circle • Luke Gallo as Rufus (season 2; guest season 3) •
Will Tudor as
Sebastian Verlac (season 2) /
Jonathan Morgenstern, Clary's older brother and the firstborn son of Jocelyn and Valentine who was injected with demon blood before his birth •
Alexandra Ordolis as Olivia "Ollie" Wilson, a former NYPD officer, Luke's former partner and Sam's girlfriend • Tara Joshi as Samantha "Sam" (season 2; guest season 3), Ollie's girlfriend • Lola Flanery and
Sarah Hyland (season 2) as the Seelie Queen, the ruler of the Seelie court who takes an interest in Simon's Daylighter status • Alyssa Capriotti as Lindsay, a nerdy Shadowhunter • Stephanie Belding as Iris Rouse, a warlock who has the ability to bring people back from the dead • Ariana Williams as Madzie, Iris's goddaughter who has a close bond with Alec and Magnus •
Noah Danby as Russell, a tough member of Luke's pack • Joanne Jansen as Gretel (season 2), another member of Luke's pack and Maia's closest friend • Neven Pajkic as Taito (season 2), a member of Luke's pack and Gretel's godfather •
Shannon Kook as Duncan (season 2), a Shadowhunter who is blackmailed by Jonathan •
Chad Connell as Quinn (season 2), a member of Raphael's clan • Erica Deutschman as Eloise (season 2), a blonde member of Raphael's clan • Andreas Apergis as Malachi Dieudonné (season 2), the Consul of the Clave who secretly works for Valentine •
Kevin Alves as Bartholomew "Bat" Velasquez, a mundane whom Russell Turns and becomes a member of the werewolf pack • Sophia Walker as Catarina Loss (guest season 2; recurring season 3), a warlock who is a close friend of Magnus and becomes Madzie's guardian • Tessa Mossey as Heidi McKenzie (guest season 2; recurring season 3), a mundane whom Simon meets at a bleeder den who is accidentally drained of blood by Quinn, another vampire • Josh Horvath as Joshua / ND Vampire, a member of the Brooklyn vampire clan and Raphael's bodyguard
Introduced in season three •
Anna Hopkins as
Lilith, a Greater Demon and the ruler of Edom •
Javier Muñoz as Lorenzo Rey, the current High Warlock of Brooklyn who happens to be jealous of Magnus •
Chai Hansen as Jordan Kyle, a mundane turned werewolf who is Maia's ex-boyfriend and the reason why Maia became a werewolf in the first place • Genevieve Kang as Morgan Young, a young woman who is briefly possessed by Lilith • Jonathan Ho as Brother Zachariach, a Silent Brother •
James McGowan as Praetor Scott, a member of the Praetor Lupus who has Luke released from prison after he falsely took credit for his pack's massacre • Brooks Darnell as Charlie Cooper, a mundane doctor •
Jack J. Yang as Asmodeus, a Greater Demon and Magnus' father •
Steve Byers as Andrew Underhill, an openly gay Shadowhunter who is the Institute's head of security •
Françoise Yip as Jia Penhallow, the current Consul of the Clave following Malachi's death and Aline's mother •
Conrad Coates as Detective Dwyer, the NYPD's lieutenant and Luke's supervisor •
Romaine Waite as Griffin, the new leader of the Brooklyn vampire clan following Raphael's banishment • Aimee Bessada as Elle, a member of Griffin's vampire clan • Pasha Ebrahimi as Cain, Abel's brother and the son of Adam and Eve •
Katie Strain as Nora Kendall, a woman who dislikes Heidi •
Luke Baines as
Jonathan Morgenstern, the restored form of Clary's brother upon his resurrection.
Will Tudor previously played Jonathan in the second season and briefly reprised the role in two episodes of the third season before the role was recast with Baines following the character's resurrection. • Kimberly-Sue Murray as the adult Seelie Queen • Kyana Teresa as Lanaia, a Seelie nymph who briefly serves Jonathan before turning on him • Jacky Lai as Aline Penhallow, Sebastian's cousin and Jia's daughter. Eileen Li previously played Aline through a guest role in the second season before the role was passed to Lai due to scheduling conflicts with the former actress. •
Sydney Meyer as Helen Blackthorn, a Shadowhunter half Seelie who starts dating Aline ==Episodes==