Shyam Nandan Mishra was an Indian independence activist and politician from Bihar. He was Member of Parliament for many years in both the Lok Sabha and Rajya Sabha. Initially a member of the Indian National Congress, he was later Leader of the Opposition in Rajya Sabha as a Congress (O) leader, and then a Janata Party MP and Minister for External Affairs in Charan Singh's government. He was imprisoned both during the Quit India Movement and the Emergency.