;S.16 :Production passenger carrier powered by a
Fiat A.12bis inline 6-cylinder engine. ;S.16bis :Improved civilian variant with reinforced hull, increased fuel capacity and a larger propeller. ;S.16bis M :Military version of the S.16bis with bow cockpit, Soviet-operated versions (80 aircraft) were designated by them the
S-16bis, some were licence-built in Spain. ;S.16ter :Improved military variant first used by the Italian Navy from 1924, powered by a
Lorraine-Dietrich 12Db V-12 piston engine. ;S.23 :Simplified variant for training, one built. ==Operators==