Simcyp Limited was acquired March 13, 2012, by Certara inc.
Simcyp Limited is a research-based company which provides modelling and simulation software to the pharmaceutical industry for use during drug development. Simcyp is based in Sheffield, UK.
Research and development
Simcyp's R&D activities focus on the development of algorithms along with population and drug databases for modelling and simulation (M&S) of the absorption and disposition of drugs in patients and specific subgroups of patients across different age ranges. The Simcyp models use experimental data generated routinely during pre-clinical drug discovery and development from in vitro enzyme and cellular systems, as well as any relevant physico-chemical attributes of the drug and dosage forms. Some details of the scientific background of Simcyp approaches can be found in recent publications. ==Background==
Background
Simcyp was originally formed as a spin-out company from the University of Sheffield, UK. The company operates the Simcyp Consortium of pharmaceutical and biotechnology companies. The Consortium acts as a steering committee, guiding scientific research and development at Simcyp. There is also close collaboration with regulatory bodies (the U.S. Food and Drug Administration, Swedish Medical Products Agency, NAM, ECVAM) and academic centres of excellence worldwide, within the framework of the Consortium. ==Simulator platforms==
Simulator platforms
Simulator platforms include the Simcyp population-based ADME Simulator, Simcyp Paediatric, Simcyp Rat, Simcyp Dog, and Simcyp Mouse. Simcyp Simulator The Simcyp Simulator is a population-based ADME simulator The functional capability of the Simcyp Simulator is summarized in the following table. ==References==