Simen Lyse started his career in Klæbu IL until he joined Charlottenlund SK in 2018. In 2020, he signed for Kolstad Håndball. In 2022/2023, Lyse won the domestic treble with
Kolstad Håndball, winning the league, the cup and the league play-offs. In the 2023/2024 season, Lyse again won the domestic triple with Kolstad Handball, winning the league, the cup and the league play-offs. In February 2025 he extended his contract with Kolstad until 2027. ==References==