The Sir Charles Tupper Building on its completion in 1960 served as the headquarters of the Department of Public Works, known by its applied title as Public Services and Procurement Canada. Public Services and Procurement Canada later moved its headquarters to Gatineau, Quebec, across the Ottawa River from Ottawa. The building also housed some Health Canada operations, notably the headquarters of the Pest Management Regulatory Agency. It was named in honour of the Father of Confederation and sixth Prime Minister of Canada. In 2023, the Government of Canada indicated that it plans to dispose of the building.