Talbot married Margaret (died 1662), the third daughter of
Sir William Talbot, 1st Baronet of
Carton, County Kildare, and his wife Alison Netterville. The marriage made him a brother-in-law of
Richard Talbot, who would later become
Earl of Tyrconnell. Henry and Margaret had two sons: •
James (died 1691), colonel in the Irish army, married Bridget Bermingham, daughter of
Francis de Bermingham, 12th Baron Athenry, and was killed at the
Battle of Aughrim • William (died 1729), his successor, married Lucy, widow of George Holmes and daughter of William Hamilton of Liscloony,
King's County —and six daughters: • Elizabeth, married
John Talbot of
Belgard Castle, County Dublin • Bridget, married Gerrit Dillon of Manin, co. Mayo • Mary (died 1691), married
Theobald Dillon, 7th Viscount Dillon and was accidentally killed during the
Siege of Limerick • Alice, married Edmund Moore of Cloonbigny, "Co. Mayo" [
recte "Co. Roscommon"]. • Ellen, married Laurence Cruise, of Cruisetown, co Meath. • Barbara, married Dominick Browne, of
Breaghwy, co. Mayo. == Later life ==