Escobar turned professional on September 1, 1930, in a
fight card organized at the Victory Garden gym in San Juan. In this event, he defeated Luis "Kid Dominican" Pérez, who entered the fight as the Dominican Republic's champion, by knockout in the third round. In Puerto Rico, Escobar fought in 15 contests, before moving to Venezuela after the popularity of professional boxing declined in his home country. In this contest he was paired against Canadian bantamweight titleholder
Bobby Leitham, defeating him by technical knockout in the seventh round. Escobar's manager, Lou Brix and his trainer recognized that Escobar could be close to a championship fight once the incumbent, Panamian
Alfonso Teófilo Brown, refused to defend the championship against the first contender, which led to it being stripped by the
National Boxing Association (NBA). He spent a month in inactivity while recovering, and in the winter he returned to Puerto Rico. However, Escobar still wasn't considered the division's
Undisputed Champion because
Balthazar Sangchili had defeated Panama Al Brown and was recognized by the IBU. Due to this, Sanstol sent a letter to the NYSAC noting that the fight was of eliminatory nature, even though it was recognized as a titular contest by the NBA and MAC. Wanting to be recognized as such, Escobar pursued a title unification fight against Tony Marino, who had defeated Sangchili by knockout in his previous fight. On April 2, 1939, Escobar defeated Kayo Morgan before a sold-out crowd of 15,000 at the
Estadio Sixto Escobar, which had been inaugurated three years earlier. Later in 1939, Escobar received a draft notice from the
United States Army, ordering him to take a physical exam for possible military service. He and his manager presented the issue to the Puerto Rico Boxing Commission, managing to receive a postponement of two months before surrendering his title. On April 6, 1940, Escobar fought Simón Chávez for ten rounds in what ended as a draw. Escobar then fought some short non-title fights, of which he lost four, all by points. On December 2, 1940, Escobar participated in his last professional fight, losing to a ten-round decision to Harry Jeffra. Throughout his career Escobar avoided being knocked down or out in any fight, all of his losses being by decision. In April 1941, he was drafted to the
United States Army and participated in
World War II obtaining the rank of
Technician fifth grade. ==Retirement, death and legacy==